Concomitant mastocytosis and juvenile xanthogranuloma.

Abstract

After hemangioma (H), mastocytosis (M) and juvenile xanthogranuloma (JX) are the most frequent self-healing proliferations of the first months of life. In our clinic we see 1 H every 20 children, 1 M in 250 children and 1 XG in1,000 children. The high frequency of H allows to find it together with M and more rarely with JX. The case described here is instead the second case since 1966 in which we see concomitant M and JX. In literature there are only 4 other cases of this rare association (1, 2, 3), which should however considered random. All 3 of these proliferations arise however in most cases in the first months of life: after a period of growth, which generally does not exceed one year of age, they begin to regress spontaneously. JX regresses faster in about 2 years, while M and H regress in a longer time.