Severe ulceration of hemangioma during treatment with oral propranolol.

Abstract

In view of the good tolerability of oral propranolol its indications in the treatment of infantile hemangioma are extending. Moreover, we tend to start the therapy early, because some observations (2) led us to believe more effective an early treatment. It is difficult to say whether in this case the regressive effects induced by propranolol favored the onset of severe ulceration, but probably the tumultuous growth of hemangioma played a favoring role. Despite the onset of severe ulceration we decided not to suspend the oral therapy with propranolol, because in other cases of deeply ulcerated hemangioma we showed (1) that oral propranolol favors the repair of ulceration much more quickly than isolated topical treatment and therapy with dye laser.