Monostotic eosinophilic granuloma.

How to Cite

Milano A., Bonifazi E. 2011. Monostotic eosinophilic granuloma. Eur. J. Pediat. Dermatol. 21 (1): 61.


Milano A. Bonifazi E.
pp. 61


A 6-year-old girl was first observed for
the presence of a frontal swelling dating from 40 days.
The physical examination showed in the right frontal
region a hemispheric swelling of about 1.5 cm, covered
by normal skin (Fig. 1). At palpation the swelling was
not very painful, had hard consistency and was adherent
to the bone layer, while the skin moved on it. The rX
showed an osteolytic image, CT (Fig. 2, 3) and RM highlighted
a mass of about 1.5 cm, infiltrating and replacing
the bone and dura mater. The bone tumor was removed
and a plastic piece of spongy bone (Tutobone ®)
was inserted with a residual scar (inset in Fig. 1). The
histological examination (Fig. 4) showed an infiltrate of
large cells with kidney-shaped nucleus and cytoplasm
with sharp borders intermingled with numerous eosinophils.
The clinical and histological data led to the final
diagnosis of monostotic eosinophilic granuloma.


Monostotic eosinophilic granuloma