Childhood pemphigus foliaceus. Self-healing seborrheic variant.

Abstract

An 8-year-old girl was visited due to exudative lesions of the upper trunk lasting a few days. The patient had already done an unsuccessfull systemic and topical antibiotic treatment. Five months later she was still affected by the same exudative lesions on the upper trunk (Fig. 1). The lesions were monomorphous, 1-2 cm in diameter, erosive, crusted or with residual hyperpigmentation. The lesion were asymptomatic except for a mild burning sensation at their onset. A cytodiagnosis examination put in evidence isolated, sometimes monstrous epidermal cells. The indirect immunofluorescence and the research of antibodies anti-desmoglein 1 and 3 and anti BP180 were negative. A biopsy was not performed mainly because the lesions completely regressed with topical corticosteroids after a 7-month comprehensive duration. The final diagnosis was childhood pemphigus foliaceus, self-healing seborrheic variant.