Lymphomatoid papulosis type B in a child.

Abstract

Lymphomatoid papulosis is a chronic-recurrent papular and nodular eruption with histological findings of lymphoma, presently included in the WHO classification of cutaneous lymphomas. About 60 cases of the latter were reported in children sometimes with a regional distribution. Three types are distinguished as follows: A, with mixed non epidermotropic infiltrate consisting of large CD30+ cells, intermingled with lymphocytes, neutrophils, eosinophils and histiocytes; B, with epidermotropic infiltrate of small or medium sized CD3+, CD30- lymphocytes; C, with monomorphous infiltrate of large CD30+ cells. Lymphomatoid papulosis may turn into lymphoma in 4% of cases for the variant with large CD30+cells in the adult. The clinical course in children is chronic, sometimes with complete regression. However, cases that developed lymphoma in the adult, even extracutaneous after 40 years, were reported.