Phylloid-Type Pigmentary Mosaicism with Transient Mast Cell Enrichment and a Darier-Like Reaction

Phylloid-type pigmentary mosaicism with transient mast cell rich enrichment

Abstract

We report a 6-month-old infant with phylloid-type pigmentary mosaicism presenting with a localized Darier-like reaction.   Histopathologic examination revealed an increased scattered dermal mast cells,  the absence of features consistent with mastocytosis and laboratory findings showed mildly elevated histamin level. Clinical reactivity and biochemical abnormality resolved during follow-up. Such findings suggest that transient mast cell enrichment within mosaic skin during infancy may represent a reactive process rather than clonal mast cell disease.